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Labels
- Age dependent Pharmacology
- Approach to the patient
- body action on drug
- Causes of diarrhea
- Common cold
- Comparison Between Type 1 and Type 2 Diabetes Mellitus
- CPR
- Diabetes Mellitus
- Diabetes Mellitus type 1
- diarrhea treatment
- drug absorption
- drug elimination
- drug excretion
- drug metabolism
- Epidemiology
- Epidimiology
- epiglottitis
- Fever.Fever Unknown Origin
- Hepatitis A
- Hepatitis a Transmission
- Hepatitis a Treatment
- High blood pressure
- Hypertension
- Infectious Diarrhea
- introduction to hypertension
- Laboratory studies
- Obesity
- Pathogenesis
- pharmacodynamic
- pharmacokinetics
- Prevalence ofThe public health cost of hypertension
- primary hypertension
- Some health complications associated with hypertension
- Sore Throat
- Symptoms
- Symptoms of diarrhea
- Total costs of hypertension
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Showing posts with label Diabetes Mellitus type 1. Show all posts
Diabetes type 1
Diabetes type 1?
Diabetes type 1 is characterized by an absolute deficiency of insulin caused by an autoimmune attack on the β cells of the pancreas. In type 1 diabetes, the islets of Langerhans become infiltrated with activated lymphocytes, leading to a condition called insulitis.
Prevalence of type 1 diabetes is 5%–10% and age of onset is <30 Years and speed of onset of type 1 diabetes is rapid as compare to type 2 diabetes and the pateints of type 1 diabetes are usually thin.
Genetics Family history uncommon
Associations. Other autoimmune diseases: Graves disease, Hashimoto thyroiditis, pernicious anemia,
Addison disease
Pathogenesis:Lack of insulin Pancreas devoid of β-islet cells Insulitis: T-cell cytokine destruction
(type IV hyper senstivity reaction) and autoantibodies against β-islet cells (>80%) and insulin (>50%) (type II HSR) Triggers for destruction—e.g., viruses
Clinical findings:Polyuria (osmotic diuresis from glucosuria), polydipsia(excessive thirst) (↑POSM), polyphagia(excessive hunger), weight loss Ketoacidosis (hyperglycemia, coma; production of ketone bodies); lactic acidosis from shock (losing sodium by osmotic diuresis from glucosuria)
Treatment: Insulin
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Diabetes Mellitus type 1,
